EXTERNAL GRANTS:
Projects currently implemented in the Department:
NCN OPUS-23, nr UMO-................. "Searching for natural bioactive farnesoid X receptor agonists and their role in parenteral nutrition-associated liver disease - in silico, in vitro and in vivo studies". Duration: 2023 - 2024.
Principal Investigator: dr hab. Maciej Stawny. Leader - Chair and Department of Pharmaceutical Chemistry, Poznan University of Medical Sciences, Poznan.
Projects previously implemented in the Department:
MNiSW/KBN N40502331/1522: “The effect of plant-derived substances on the activity of enzymes metabolizing drugs from the cytochrome P450 family”. Duration: 2005-2008.
Principal Investigator: doc. dr hab. P.M. Mrozikiewicz. Leader - Institute of Natural Fibers and Medicinal Plants, Poznań.
MNiSW/KBN 2P05F03228: “Research on increasing the production efficiency of secondary metabolites with activity stimulating the central nervous system in the roseroot biomass (Rhodiola rosea L.) obtained in in vitro culture in a bioreactor”. Duration: 2005 - 2008.
Principal Investigator: dr A. Krajewska-Patan. Leader - Institute of Natural Fibers and Medicinal Plants, Poznań.
MNiSW/KBN N40502432/1684: „The role of endogenous opioids in the central mechanism of alcoholic action of Pueraria lobata (kudzu)”. Duration: 2007 - 2009.
Principal Investigator: dr hab. Przemysław Mikołajczak. Leader - Department of Pharmacology, Poznan University of Medical Sciences, Poznan.
MNiSW/KBN N40502532/1687: „Secondary metabolites of Rhodiola Kirilowii (Regel.) Maxim in in vitro culture compared to cultivation in soil - variability of active compounds content and their biological activity focused on the symptoms of hypoxia”. Duration: 2007 - 2011.
Principal Investigator: dr A. Krajewska-Patan. Leader - Institute of Natural Fibers and Medicinal Plants, Poznań.
MNiSW/KBN N405101934: „Effect of Epilobium angustifolium and Serenoa repens extracts on the expression of genes related to the pathogenesis of benign prostatic hyperplasia”. Duration: 2008 - 2010.
Principal Investigator: doc. dr hab. P.M. Mrozikiewicz. Leader - Institute of Natural Fibers and Medicinal Plants, Poznań.
MNiSW/KBN N405417836: “Medicinal plants of the Lamiaceae family in Alzheimer's disease – a model study”. Leader: 2008 - 2011.
Principal Investigator: dr hab. Marcin Ożarowski. Leader - Institute of Natural Fibers and Medicinal Plants, Poznań.
MNiSW/KBN - N405358737: “The role of ghrelin in assessing the effectiveness of anti-alcoholic agents”. Duration: 2009 - 2011.
Principal Investigator: dr Michał Szulc. Leader - Department of Pharmacology, Poznan University of Medical Sciences, Poznan.
MNiSW/KBN - N402357638: “Selected non-classical proatherogenic factors in people with type 2 diabetes in the aspect of pharmacotherapy”. Duration: 2010 - 2012.
Principal Investigator: dr Magdalena Borowska. Leader - Department of Pharmacology, Poznan University of Medical Sciences, Poznan.
NCN N405677140: “The effect of plant-derived substances and synthetic drugs on the level of MDR1, MRP1, MRP2 gene expression and genes encoding OATP family factors determining blood-brain barrier activity“. Duration: 2011-2013.
Principal Investigator: Prof. P.M. Mrozikiewicz. Department of Clinical Pharmacy and Biopharmacy, Poznan University of Medical Sciences, Poznan.
MNiSW/KBN/NCN N405219539: „Preparation of raw materials and extracts from large-scale globose (Platycodon grandiflorum A.DC.) and their phytochemical analysis and assessment of the effect of standardized extracts on selected factors associated with the pathogenesis of chronic bronchitis in rats”. Duration: 2010 - 2013.
Principal Investigator: Prof. INF&NP dr hab. W. Buchwald. Leader - Institute of Natural Fibers and Medicinal Plants, Poznań.
MNiSW/KBN/NCN N405677740: “Biological and pharmacological studies of protein fractions and non-protein extracts from Chelidonium majus L., using raw materials derived from soil cultivation and in vitro cultures”. Duration: 2011 - 2014.
Principal Investigator: Prof. INF&NP dr hab. B. Kędzia. Leader - Institute of Natural Fibers and Medicinal Plants, Poznań.
MNiSW NN405 678040: “Comparative study of anti-alcoholic activity of extracts of Salvia miltiorrhiza and Salvia przewalskii obtained from field cultivation and in vitro culture". Duration: 20011-2014.
Principal Investigator: Prof. Przemysław Mikołajczak. Leader - Institute of Natural Fibers and Medicinal Plants, Poznań.
NCBIR INNOMED/I/11/NCBR/2014: Onkokan „"Development of technology for acquiring cannabinoids from hemp with a low THC content as a means of supporting the treatment of oncological patients”. Duration: 2014 - 2018.
Principal Investigator: Prof. Ryszard Słomski. Leader - Poznan University of Medical Sciences, Poznan.
NCN Miniatura -1, nr 2017/01/X/NZ7/02041. "Cannabidiol as a modulator of the development of alcohol tolerance in rats - aspects of molecular in vivo activity as a key stage of pharmacodynamic studies". Duration: 2018 year.
Principal Investigator: dr Michał Szulc. Leader - Department of Pharmacology, Poznan University of Medical Sciences, Poznan.
NCN OPUS, nr UMO-2017/25/B/NZ7/02741. "The role of flavonoids in the development of pregnancy-induced hypertension - in vitro and in vivo studies". Okres: 2018 - 2020 r.
Principal Investigator: Prof. Agnieszka Seremak-Mrozikiewicz. Leader - Institute of Natural Fibers and Medicinal Plants, Poznań.
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INTERNAL PROJECTS
(the stage of which is at least partially conducted outside the Department)
“Changes in the expression of genes encoding selected representatives of phase II enzymes of the xenobiotics biotransformation in the liver of rats with induced alcohol tolerance”; Budget: the statutory activity of the Department.
Planned period: 10-12.2021.
Place of study: Poznan University of Medical Sciences Core Facility.
